The indication of ulipristal acetate 5mg for uterine fibroids has been further restricted due to the risk of serious liver injury and liver failure, with some cases requiring liver transplantation. Although the temporary sus…
Published: 2021-02-18T11:36:51Z
Pregabalin has been associated with infrequent reports of severe respiratory depression, including some cases without the presence of concomitant opioid medicines. Patients with compromised respiratory function, respiratory …
Published: 2021-02-18T11:36:41Z
When children receiving replacement therapy for adrenal insufficiency are being switched from hydrocortisone tablets to Alkindi granules, parents or carers should be informed of the need to be extra vigilant for symptoms of …
Published: 2021-02-18T11:36:23Z
Information on the newly launched Safer Medicines in Pregnancy and Breastfeeding Consortium and a new report on optimising data on medicines used during pregnancy.
Published: 2021-02-18T11:36:03Z
A summary of advice recently issued by the MHRA relating to coronavirus (COVID-19), up to 16 February 2021.
Published: 2021-02-18T11:35:48Z
A summary of letters and drug alerts recently sent to healthcare professionals.
Published: 2021-02-18T11:34:55Z
A review of the risks of major congenital malformations and of adverse neurodevelopmental outcomes for antiepileptic drugs by the Commission on Human Medicines has confirmed that lamotrigine (Lamictal) and levetiracetam (K…
Published: 2021-01-07T11:02:01Z
Recent advice from the MHRA on the COVID-19 vaccines authorised for use in the UK, including advice for people with allergies and for women during pregnancy and breastfeeding.
Published: 2021-01-07T11:01:19Z
The monitoring requirements and discontinuation criteria for dimethyl fumarate (Tecfidera) have been strengthened following a small number of reports of progressive multifocal leukoencephalopathy (PML) in patients with mild …
Published: 2021-01-07T11:01:04Z
Liver monitoring requirements and discontinuation criteria for fingolimod have been updated following reports of serious liver injury. Fatal cases of encephalitis and meningitis caused by herpes simplex and varicella zoster …
Published: 2021-01-07T11:00:51Z